| ncRNA name | HIF-1α siRNA |
| ncRNA Category | siRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell line Y79 |
| Methods | siRNA transfection, RT-PCR, Western blot |
| Expression pattern | associated |
| Functional description | Knockdown of HIF-1α by siRNAHIF-1α resulted in inhibition of cell proliferation and induced cell apoptosis in human Y-79 RB cells under both normoxic and hypoxic conditions, with hypoxic conditions being more sensitive. |
| PubMed ID | 24860939 |
| Year | 2014 |
| Title | Inhibition of hypoxia inducible factor 1α by siRNA-induced apoptosis in human retinoblastoma cells. |
| Drug-related ncRNA | NO |
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